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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK1
All Species:
24.24
Human Site:
T335
Identified Species:
44.44
UniProt:
Q96SB4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB4
NP_003128.3
655
74325
T335
E
K
L
E
E
S
S
T
I
G
Q
D
Q
T
L
Chimpanzee
Pan troglodytes
XP_518428
831
92792
T511
E
K
L
E
E
S
S
T
I
G
Q
D
Q
T
F
Rhesus Macaque
Macaca mulatta
XP_001116721
831
92803
T511
E
K
L
E
E
S
S
T
I
G
Q
D
Q
T
L
Dog
Lupus familis
XP_850330
823
92006
T503
E
K
L
E
E
S
S
T
I
D
Q
D
Q
T
L
Cat
Felis silvestris
Mouse
Mus musculus
O70551
648
73070
S335
E
K
L
E
E
S
N
S
I
G
Q
D
Q
T
L
Rat
Rattus norvegicus
NP_001020897
655
73837
S335
E
K
L
E
E
S
S
S
I
G
Q
D
Q
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516210
528
59280
L261
N
V
G
E
T
Q
G
L
A
Q
E
Q
T
N
F
Chicken
Gallus gallus
XP_419265
754
84415
K426
K
K
K
G
M
D
Q
K
Y
S
E
V
I
V
R
Frog
Xenopus laevis
NP_001085122
605
68633
P318
W
T
E
S
G
S
E
P
N
C
N
G
L
T
S
Zebra Danio
Brachydanio rerio
NP_001074138
640
71523
S315
D
S
T
P
S
V
P
S
S
H
T
L
Q
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
Q443
V
W
L
A
W
D
T
Q
D
K
R
F
V
A
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
V160
D
K
G
G
N
R
C
V
Q
I
R
N
W
F
D
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
S410
M
R
A
H
F
C
G
S
S
H
N
S
F
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
78.2
76.7
N.A.
91.4
91.4
N.A.
65.5
70.1
67.6
64.7
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
100
78.6
78.5
77.6
N.A.
94.6
94
N.A.
70.3
77.3
78.1
76.1
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
100
93.3
100
93.3
N.A.
86.6
93.3
N.A.
6.6
6.6
13.3
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
100
100
N.A.
13.3
20
13.3
26.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
8
0
0
8
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
16
0
0
8
8
0
47
0
8
8
% D
% Glu:
47
0
8
54
47
0
8
0
0
0
16
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
8
8
8
16
% F
% Gly:
0
0
16
16
8
0
16
0
0
39
0
8
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
16
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
47
8
0
0
8
0
8
% I
% Lys:
8
62
8
0
0
0
0
8
0
8
0
0
0
0
0
% K
% Leu:
0
0
54
0
0
0
0
8
0
0
0
8
8
0
39
% L
% Met:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
8
0
8
0
8
0
16
8
0
8
0
% N
% Pro:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
8
8
8
47
8
54
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
0
0
16
0
0
0
8
% R
% Ser:
0
8
0
8
8
54
39
31
16
8
0
8
0
8
16
% S
% Thr:
0
8
8
0
8
0
8
31
0
0
8
0
8
54
0
% T
% Val:
8
8
0
0
0
8
0
8
0
0
0
8
8
8
0
% V
% Trp:
8
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _